Cheap flights from Knoxville to San Francisco (TYS - SFO) from $110

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/17. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
TYS — SFO
May 20 — May 271

The best prices from Knoxville McGhee Tyson to San Francisco are usually found in February or September, booked 47 days in advance, depart on a Wednesday or Tuesday and return on a Monday

Cheap flight deals from Knoxville to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 15, 2024.

Popular in

March

Cheapest in

February

Round-trip from

$267

One-way from

$254
High demand for flights, 8% potential price rise
Best time to find cheap flights, 21% potential price drop
From Knoxville McGhee Tyson to San Francisco
One-way flight from Knoxville McGhee Tyson to San Francisco

What is the cheapest day to fly round-trip from Knoxville to San Francisco?

Sunday flights are generally found to be more expensive for flights from Knoxville to San Francisco. This shouldn’t discourage you from searching, as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to San Francisco.

How far in advance should I book a flight from Knoxville to San Francisco?

To save on the cost of your flight from Knoxville to San Francisco, book at least 48 days before your planned departure. Booking around this time can save you about 71% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $416 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $705.

What is the cheapest month to fly from Knoxville to San Francisco?

February can be a great time to fly to San Francisco from Knoxville with a flight ticket averaging about $508. Cheapflights users have found deals in the month of February for as cheap as $260. The most expensive prices can be found in the month of March.

When is the cheapest time to fly from Knoxville to San Francisco (TYS - SFO)?

One of the essential ways to save on airfare from Knoxville to San Francisco is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 25% on airfare.

Cheap Delta flights from Knoxville to San Francisco

Explore cheap flight options specifically provided by Delta for the route between Knoxville and San Francisco. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 2,632,958 searches. Data last updated May 15, 2024.
Take a look at some of the lowest-priced Delta flights heading from Knoxville to San Francisco. Deals update often to give you more flight options matching your criteria
Tue 8/206:45 amTYS - SFO
1 stop9h 47mDelta
Sat 8/2411:50 pmSFO - TYS
1 stop6h 30mDelta
Deal found 5/13$327
Tue 8/202:30 pmTYS - SFO
1 stop7h 02mDelta
Fri 8/2312:25 amSFO - TYS
1 stop19h 35mDelta
Deal found 5/13$411
Thu 5/2311:16 amTYS - SFO
1 stop9h 17mDelta
Mon 5/2710:45 pmSFO - TYS
1 stop8h 26mDelta
Deal found 5/13$448
Sat 9/217:15 amTYS - SFO
1 stop10h 15mDelta
Wed 9/255:45 pmSFO - TYS
2 stops12h 25mDelta
Deal found 5/14$675
Wed 5/293:49 pmTYS - SFO
1 stop9h 33mDelta
Mon 6/310:55 amSFO - TYS
2 stops9h 56mDelta
Deal found 5/14$736
Thu 6/67:10 pmTYS - SFO
1 stop8h 12mDelta
Tue 6/117:03 pmSFO - TYS
2 stops11h 23mDelta
Deal found 5/14$796
Fri 5/317:14 pmTYS - SFO
1 stop7h 08mDelta
Tue 6/412:40 amSFO - TYS
2 stops9h 53mDelta
Deal found 5/14$981
Sun 5/195:30 amTYS - SFO
2 stops9h 50mDelta
Wed 5/226:00 amSFO - TYS
1 stop8h 55mDelta
Deal found 5/14$1,006
Thu 5/235:30 amTYS - SFO
2 stops9h 50mDelta
Mon 5/278:55 pmSFO - TYS
2 stops10h 16mDelta
Deal found 5/13$1,009

Cheap Frontier flights from Knoxville to San Francisco

Explore cheap flight options specifically provided by Frontier for the route between Knoxville and San Francisco. Find affordable fares and compare prices with other airlines to secure the best deal for your journey. Over the last 7 days, Cheapflights users made 2,632,958 searches. Data last updated May 15, 2024.
Some of the best deals we've found on Frontier flights traveling from Knoxville to San Francisco. Ensure the flight price, dates, time, and airline match your criteria before you book.
Wed 7/246:17 pmTYS - SFO
1 stop16h 25mFrontier
Tue 7/3012:58 amSFO - TYS
1 stop13h 19mFrontier
Deal found 5/14$217
Fri 5/314:01 pmTYS - SFO
1 stop10h 58mFrontier
Tue 6/412:59 amSFO - TYS
1 stop14h 48mFrontier
Deal found 5/14$286
Sat 9/215:40 pmTYS - SFO
1 stop9h 18mFrontier
Tue 9/2412:58 amSFO - TYS
1 stop13h 19mFrontier
Deal found 5/14$288
Mon 5/276:35 pmTYS - SFO
1 stop8h 24mFrontier
Fri 5/3112:59 amSFO - TYS
1 stop12h 09mFrontier
Deal found 5/13$333
Mon 5/276:35 pmTYS - SFO
2 stops30h 27mFrontier
Fri 5/3112:59 amSFO - TYS
1 stop12h 09mFrontier
Deal found 5/13$338
Mon 5/276:35 pmTYS - SFO
1 stop8h 24mFrontier
Fri 5/3112:59 amSFO - TYS
1 stop12h 09mFrontier
Deal found 5/14$345
Fri 9/135:42 pmTYS - SFO
1 stop17h 31mFrontier
Sun 9/1512:58 amSFO - TYS
1 stop13h 19mFrontier
Deal found 5/14$348
Mon 5/276:35 pmTYS - SFO
2 stops20h 51mFrontier
Fri 5/3112:59 amSFO - TYS
1 stop12h 09mFrontier
Deal found 5/14$355
Wed 6/127:47 pmTYS - SFO
1 stop14h 00mFrontier
Sun 6/2312:59 amSFO - TYS
1 stop17h 40mFrontier
Deal found 5/14$385

Cheap Knoxville to San Francisco flights in May & June 2024

Find cheap flight options from Knoxville to San Francisco specifically for the months of May and June 2024. Explore affordable fares based on user searches. Over the last 7 days, Cheapflights users made 2,632,958 searches. Prices were last updated on May 15, 2024.
Scroll through some of the best deals on flights from Knoxville to San Francisco in 2024. If these deals don't appeal to you, be sure to come back soon for more options.
Mon 5/276:35 pmTYS - SFO
2 stops30h 27mFrontier
Fri 5/3112:59 amSFO - TYS
1 stop12h 09mFrontier
Deal found 5/13$338
Mon 5/276:35 pmTYS - SFO
1 stop8h 24mFrontier
Fri 5/3112:59 amSFO - TYS
1 stop12h 09mFrontier
Deal found 5/14$345
Mon 5/276:35 pmTYS - SFO
2 stops20h 51mFrontier
Fri 5/3112:59 amSFO - TYS
1 stop12h 09mFrontier
Deal found 5/14$355
Wed 5/295:58 pmTYS - SFO
1 stop8h 09mAmerican Airlines
Mon 6/311:52 pmSFO - TYS
1 stop7h 45mAmerican Airlines
Deal found 5/14$365
Fri 5/316:31 pmTYS - SFO
1 stop8h 50mAmerican Airlines
Wed 6/51:43 pmSFO - TYS
1 stop7h 41mAmerican Airlines
Deal found 5/14$368
Wed 6/125:12 amTYS - SFO
1 stop9h 54mAmerican Airlines
Mon 6/2411:57 pmSFO - TYS
1 stop8h 17mAmerican Airlines
Deal found 5/14$372
Wed 6/127:47 pmTYS - SFO
1 stop14h 00mFrontier
Sun 6/2312:59 amSFO - TYS
1 stop17h 40mFrontier
Deal found 5/14$385
Wed 6/127:47 pmTYS - SFO
1 stop7h 22mFrontier
Tue 6/1812:59 amSFO - TYS
1 stop14h 48mFrontier
Deal found 5/14$398
Sun 5/265:50 amTYS - SFO
1 stop8h 11mUnited Airlines
Sat 6/15:00 amSFO - TYS
1 stop8h 13mUnited Airlines
Deal found 5/14$413

Knoxville to San Francisco 2024 flight deals

Discover exclusive flight deals for travel between Knoxville and San Francisco in 2024. Find excellent offers based on user searches. Over the last 7 days, Cheapflights users made 2,632,958 searches. Data last updated May 15, 2024.
Scroll through some of the best deals on flights from Knoxville to San Francisco in 2024. If these deals don't appeal to you, be sure to come back soon for more options.
Mon 5/276:35 pmTYS - SFO
2 stops30h 27mFrontier
Fri 5/3112:59 amSFO - TYS
1 stop12h 09mFrontier
Deal found 5/13$338
Mon 5/276:35 pmTYS - SFO
1 stop8h 24mFrontier
Fri 5/3112:59 amSFO - TYS
1 stop12h 09mFrontier
Deal found 5/14$345
Tue 8/209:25 amTYS - SFO
1 stop7h 42mUnited Airlines
Sat 8/241:05 pmSFO - TYS
1 stop7h 25mUnited Airlines
Deal found 5/14$348
Mon 5/276:35 pmTYS - SFO
2 stops20h 51mFrontier
Fri 5/3112:59 amSFO - TYS
1 stop12h 09mFrontier
Deal found 5/14$355
Mon 7/156:17 pmTYS - SFO
1 stop16h 08mFrontier
Fri 7/197:42 pmSFO - TYS
1 stop18h 08mFrontier
Deal found 5/14$360
Wed 5/295:58 pmTYS - SFO
1 stop8h 09mAmerican Airlines
Mon 6/311:52 pmSFO - TYS
1 stop7h 45mAmerican Airlines
Deal found 5/14$365
Fri 5/316:31 pmTYS - SFO
1 stop8h 50mAmerican Airlines
Wed 6/51:43 pmSFO - TYS
1 stop7h 41mAmerican Airlines
Deal found 5/14$368
Wed 6/125:12 amTYS - SFO
1 stop9h 54mAmerican Airlines
Mon 6/2411:57 pmSFO - TYS
1 stop8h 17mAmerican Airlines
Deal found 5/14$372
Wed 6/127:47 pmTYS - SFO
1 stop14h 00mFrontier
Sun 6/2312:59 amSFO - TYS
1 stop17h 40mFrontier
Deal found 5/14$385

Knoxville to San Francisco flights leaving soon

Find last-minute flight options from Knoxville to San Francisco for spontaneous travel. Discover available flights and compare prices based on user searches. Secure great deals and offers for spontaneous trips with quick booking options. Over the last 7 days, Cheapflights users made 2,632,958 searches. Data last updated May 15, 2024.
Users seeking a last-minute flight from Knoxville to San Francisco should consider booking one of these fares. Users should examine the flight details to ensure there are no surprises.
Thu 5/2311:16 amTYS - SFO
1 stop9h 17mDelta
Mon 5/2710:45 pmSFO - TYS
1 stop8h 26mDelta
Deal found 5/13$448
Thu 5/235:40 pmTYS - SFO
1 stop10h 19mUnited Airlines
Sun 5/2612:30 amSFO - TYS
1 stop9h 56mUnited Airlines
Deal found 5/13$698
Thu 5/237:00 amTYS - SFO
2 stops13h 45mUnited Airlines
Mon 5/2710:35 pmSFO - TYS
1 stop8h 42mUnited Airlines
Deal found 5/13$766
Thu 5/237:00 amTYS - SFO
2 stops13h 45mUnited Airlines
Sun 5/2612:30 amSFO - TYS
1 stop9h 56mUnited Airlines
Deal found 5/13$811
Sun 5/197:01 amTYS - SFO
1 stop8h 46mAmerican Airlines
Wed 5/2211:52 pmSFO - TYS
1 stop7h 45mAmerican Airlines
Deal found 5/14$815
Sun 5/195:30 amTYS - SFO
2 stops9h 50mDelta
Wed 5/226:00 amSFO - TYS
1 stop8h 55mDelta
Deal found 5/14$1,006
Thu 5/235:30 amTYS - SFO
2 stops9h 50mDelta
Mon 5/278:55 pmSFO - TYS
2 stops10h 16mDelta
Deal found 5/13$1,009
Sun 5/195:30 amTYS - SFO
2 stops11h 20mAmerican Airlines
Wed 5/229:05 amSFO - TYS
2 stops11h 46mAmerican Airlines
Deal found 5/14$1,062
Sun 5/197:00 amTYS - SFO
1 stop8h 12mUnited Airlines
Tue 5/2112:09 amSFO - TYS
1 stop7h 07mUnited Airlines
Deal found 5/14$1,203

One-way flights to San Francisco from Knoxville

Search for one-way flight options from Knoxville to San Francisco. Find affordable one-way fares based on user searches. Compare prices and availability to plan your one-way journey according to your preferred dates and budget. Over the last 7 days, Cheapflights users made 2,632,958 searches. Data last updated May 15, 2024.
Users traveling one-way from Knoxville to San Francisco can select one of these great deals. Users in need of a round-trip flight from Knoxville to San Francisco instead should update the search form at the top of page.
Wed 7/176:17 pmTYS - SFO
1 stop8h 41mFrontier
Deal found 5/14$110
Mon 8/126:17 pmTYS - SFO
1 stop8h 41mFrontier
Deal found 5/14$120
Mon 5/206:38 pmTYS - SFO
1 stop15h 21mFrontier
Deal found 5/14$169
Mon 8/127:15 amTYS - SFO
2 stops18h 41mMultiple Airlines
Deal found 5/14$216
Mon 8/1211:49 amTYS - SFO
3 stops14h 07mMultiple Airlines
Deal found 5/14$230
Wed 7/176:34 pmTYS - SFO
2 stops25h 51mMultiple Airlines
Deal found 5/14$231
Thu 6/136:00 amTYS - SFO
2 stops19h 52mMultiple Airlines
Deal found 5/14$254
Thu 6/132:43 pmTYS - SFO
1 stop9h 13mAmerican Airlines
Deal found 5/14$268
Mon 5/206:38 pmTYS - SFO
2 stops20h 48mFrontier
Deal found 5/14$295

Find flights from Knoxville to San Francisco within your budget

Customize your flight search to find flights from Knoxville to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,632,958 searches. Data last updated May 15, 2024.

Fly from

Any airport

Fly to

Any airport

Budget

$217 - $539

Route

Depart

Return

Price

Knoxville McGhee TysonSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Wed 7/24

1 stop16h 25m

San Francisco

Tue 7/30

1 stop13h 19m

$217

Knoxville McGhee TysonSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Sat 9/21

1 stop10h 31m

San Francisco

Wed 9/25

1 stop8h 29m

$245

Knoxville McGhee TysonSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Thu 9/19

1 stop9h 02m

San Francisco

Tue 9/24

1 stop6h 47m

$277

Knoxville McGhee TysonSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Thu 9/19

1 stop9h 01m

San Francisco

Mon 9/23

1 stop9h 33m

$278

Knoxville McGhee TysonSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Fri 5/31

1 stop10h 58m

San Francisco

Tue 6/4

1 stop14h 48m

$286

Knoxville McGhee TysonSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Sat 9/21

1 stop9h 18m

San Francisco

Tue 9/24

1 stop13h 19m

$288

Knoxville McGhee TysonSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Tue 8/20

1 stop9h 47m

San Francisco

Sat 8/24

1 stop6h 30m

$327

Knoxville McGhee TysonSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Sun 5/26

1 stop8h 11m

San Francisco

Sat 6/1

1 stop8h 13m

$413

Knoxville McGhee TysonSan Francisco

TYS - SFO

TYSSFO

Knoxville McGhee Tyson

Mon 5/27

3 stops22h 02m

San Francisco

Sat 6/1

2 stops17h 17m

$539

Flights are sorted by cheapest first

Deals found on 5/14

When is the best time to book a flight from Knoxville to San Francisco?

Use this chart to determine the optimal time to book a round-trip flight from Knoxville to San Francisco. Price data was last updated on May 10, 2024.
The best time to book flights from Knoxville to San Francisco is 47 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Search Deals

When is the cheapest time to fly from Knoxville to San Francisco?

Use this chart to determine the cheapest time to fly round-trip from Knoxville to San Francisco. Price data was last updated on May 5, 2024.
Morning
Noon
Afternoon
Evening
All times are departure.
Travelers seeking maximum savings on their Knoxville to San Francisco flight should consider departing on Monday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Search Deals

Average price of flights to San Francisco by month

Plan your trip from Knoxville to San Francisco by taking into account the cheapest months to travel. The average price of a one-way flight from Knoxville to San Francisco is currently $210 while a round-trip flight costs $319. Price data was last updated on May 12, 2024.

Currently, December is the cheapest month in which you can book a flight from Knoxville to San Francisco (average of $267). Flying from Knoxville to San Francisco in June is currently the most expensive (average of $382). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

January

$274

February

$281

March

$330

April

$296

May

$316

June

$382

July

$364

August

$298

September

$268

October

$268

November

$287

December

$267

Temperature and rainfall in San Francisco by month

Plan your trip to San Francisco by taking into account the average temperature and rainfall totals by month.

SFO

Temperature

51.8 - 62.6 °F

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated May 15, 2024.
Read reviews from past customers who have flown Delta, Frontier and American Airlines from Knoxville to San Francisco. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good
10,706 reviews

Boarding

8.2

Crew

8.6

Overall

8.0

Entertainment

8.0

Comfort

7.9

Food

7.4

Reviews

1 / 10

Crew was nice and courteous. Boarding went smoothly. But we experienced a few minutes of extreme turbulence.

8.0
Very good
10,706 reviews
8.0
Very good
10,706 reviews

Boarding

8.2

Crew

8.6

Overall

8.0

Entertainment

8.0

Comfort

7.9

Food

7.4

Reviews

1 / 10

Crew was nice and courteous. Boarding went smoothly. But we experienced a few minutes of extreme turbulence.

7.4
Good
10,959 reviews
8.0
Very good
10,706 reviews

Boarding

8.2

Crew

8.6

Overall

8.0

Entertainment

8.0

Comfort

7.9

Food

7.4

Reviews

1 / 10

Crew was nice and courteous. Boarding went smoothly. But we experienced a few minutes of extreme turbulence.

7.3
Good
14,561 reviews
8.0
Very good
10,706 reviews

Boarding

8.2

Crew

8.6

Overall

8.0

Entertainment

8.0

Comfort

7.9

Food

7.4

Reviews

1 / 10

Crew was nice and courteous. Boarding went smoothly. But we experienced a few minutes of extreme turbulence.

6.3
Okay
4,073 reviews
8.0
Very good
10,706 reviews

Boarding

8.2

Crew

8.6

Overall

8.0

Entertainment

8.0

Comfort

7.9

Food

7.4

Reviews

1 / 10

Crew was nice and courteous. Boarding went smoothly. But we experienced a few minutes of extreme turbulence.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • Can I find flights from Knoxville to San Francisco for under $300 on Cheapflights?

    Yes, there are multiple flights from Knoxville to San Francisco for under $300. The cheapest flight booked recently is on Frontier for just $217, but on average you can expect to pay $332.

  • Are there last-minute flights available from Knoxville to San Francisco for under $500?

    There are currently 12+ open flights from Knoxville to San Francisco within the next 7 days for less than $500.

  • What are the cheapest airlines flying from Knoxville to San Francisco round-trip?

    Flying on Frontier is currently your cheapest option to San Francisco, with prices starting at $217. Additional round-trip tickets that might be worth considering are offered by American Airlines and Delta, with the lowest prices starting at $245 and $327, respectively. Frontier is priced at 57% lower than the current average price of a flight leaving 3 months from now.

  • What are the most popular airlines that fly from Knoxville to San Francisco?

  • What does TYS to SFO mean?

    TYS and SFO are unique codes to identify airports used in the aviation industry. They are defined by IATA (International Air Transport Association) and are commonly called IATA codes. TYS to SFO refers to a flight route from Knoxville McGhee Tyson Airport to San Francisco Airport.

  • Can I find deals for flights from Knoxville to San Francisco that include extra baggage allowance?

    The amount of baggage you can bring on your Knoxville to San Francisco flight depends on the airline and the type of fare you've chosen. After entering your flight details, you'll be able to view the specific baggage policies for each deal in the search results. Keep in mind that certain deals may offer additional baggage allowance.

  • Can I find deals on flights from Knoxville to San Francisco with specific airlines?

    Yes, Cheapflights allows you to browse and filter Knoxville to San Francisco flight deals by airline. After entering your origin and destination, use the available filters to view flights offered by airlines.

  • Can I find deals for flights from Knoxville to San Francisco that include hotel bookings?

    Yes. In addition to deals on Knoxville to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to San Francisco.

  • Can I find deals for business class flights from Knoxville to San Francisco?

    Yes. Cheapflights offers flight deals from Knoxville to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • Can I find deals for flights from Knoxville to San Francisco that allow pets onboard?

    Many airlines flying from Knoxville to San Francisco offer the option to travel with pets. After selecting a flight deal, you can find more information about the airline's pet policy on their official website or by contacting the airline directly. Please note that additional fees and restrictions may apply.

  • Can I find deals on last-minute flights from Knoxville to San Francisco?

    Yes, you can often find last-minute deals on Knoxville to San Francisco flights on Cheapflights. However, these deals can vary and may not always be available. We recommend checking back frequently or signing up for price alerts for the most up-to-date deals.

  • How recently were the Knoxville to San Francisco flight deals updated?

    The Knoxville to San Francisco flight deals you see on this page were last updated on 5/14.

See more FAQs

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Alternative routes for Knoxville to San Francisco
See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Knoxville to San Francisco

Discover the top 4 airlines that operate flights from Knoxville to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,632,958 searches. Data last updated May 15, 2024.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$183Average$276FlexibilityNo cancel feeOn-time62%
Search Frontier flights
DeltaCheapest$266Average$477FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
American AirlinesCheapest$304Average$504FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
United AirlinesCheapest$367Average$632FlexibilityNo cancel feeOn-time69%
Search United Airlines flights

Search flights from Knoxville to San Francisco by cabin class

Find flights from Knoxville to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Fly with Cheapflights

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How does Cheapflights help users find flights from Knoxville to San Francisco?

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Cheapflights helps you find that perfect flight to San Francisco from Knoxville by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

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